This is a 25-minute clip/interview where he passionately defends his (and Carlton Cuse's) vision for the Lost finale, why he felt it was appropriate, why some things needed to be left unexplained, why he has no regrets,etc. It's at
theverge.com.
Note: this is the man who is (co) writing the next Star Trek film, explaining why he trusts his own vision and creativity and understanding.